Status:
COMPLETED
Metabolic Fate Modifications of Saturated Fats After an Overfeeding
Lead Sponsor:
Centre de Recherche en Nutrition Humaine Rhone-Alpe
Collaborating Sponsors:
Institut National de la Santé Et de la Recherche Médicale, France
Conditions:
Obesity
Lipid Metabolism
Eligibility:
MALE
18-55 years
Phase:
NA
Brief Summary
The purpose of this study is to determine the partitioning of exogenous lipids in the postprandial period while a study of overfeeding. The method is based on the incorporation of a stable isotopic tr...
Detailed Description
Healthy overweight and lean young men are subjected to an overfeeding during 56 days which corresponds to a supplement of 761 Kcal/day. During two exploration days (before : D0 et after : D56 overfeed...
Eligibility Criteria
Inclusion
- 18 to 55 years old
- BMI 18 to 30 kg/m²
- Stable physical activity
- Safety subject during medical consultation
Exclusion
- Medical or surgical history which may affect energy expenditure (renal -cardiovascular -hepatic- endocrine-inflammatory diseases)
- Drug use that could affect energy expenditure (steroids, nicotine substitutes, thyroid hormones)
- Eating disorder
- Intensive sportive activity
- Subjects who Smoke
- Claustrophobic subjects
Key Trial Info
Start Date :
September 1 2005
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
March 1 2010
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT00905892
Start Date
September 1 2005
End Date
March 1 2010
Last Update
June 23 2011
Active Locations (1)
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1
Centre de recherche en nutrition humaine Rhone-Alpes
Pierre-Bénite, France, 69495