Status:
UNKNOWN
Propofol and Fentanyl Versus Midazolam and Fentanyl for Endoscopy Sedation in Cirrhotic Patients
Lead Sponsor:
Federal University of São Paulo
Conditions:
Cirrhosis
Eligibility:
All Genders
18-75 years
Phase:
PHASE4
Brief Summary
The purpose of this study is to compare propofol associated with fentanyl versus midazolam plus fentanyl for sedation during diagnosis or therapeutic upper gastrointestinal endoscopy (UGE) in cirrhoti...
Detailed Description
UGE is often performed in cirrhotic patients for the diagnosis and treatment of portal hypertension complications. Current data suggests that propofol sedation may have advantages over benzodiazepines...
Eligibility Criteria
Inclusion
- Liver cirrhosis, any etiology
- ASA II or III
- Child A, B or C
- Age between 18 years and 75 years
- Patients that agree in participate of study and signed the contentment term
Exclusion
- Schistosomiasis
- Recuse
- Hepatocellular carcinoma
- Contraindications to drugs
- ASA IV or V
- Hepatic encephalopathy, neurologic diseases
- Opioids, narcotics, MAO inhibitors or benzodiazepines use
- Alcohol abuse
Key Trial Info
Start Date :
March 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 1 2009
Estimated Enrollment :
210 Patients enrolled
Trial Details
Trial ID
NCT00906139
Start Date
March 1 2008
End Date
November 1 2009
Last Update
May 25 2009
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Federal University of São Paulo
São Paulo, São Paulo, Brazil, 04024-002