Status:
WITHDRAWN
Aggressive Versus Conservative Blood Glucose Control in Hospitalized Type 2 Diabetic Patients Using Detemir and Aspart Insulin
Lead Sponsor:
University of Texas Southwestern Medical Center
Collaborating Sponsors:
Novo Nordisk A/S
Conditions:
Type 2 Diabetes
Eligibility:
All Genders
18-65 years
Phase:
PHASE4
Brief Summary
The purpose of this study is to determine whether aggressive (goal pre-prandial blood glucose \<110 mg/dl) versus conservative (goal pre-prandial blood glucose \<180mg/dl) diabetes treatment of type 2...
Detailed Description
Objective: The objective of this study is to determine the effect of an "aggressive" blood glucose control (goal pre-prandial CBG \<110 mg/dl) versus a "conservative" blood glucose control (goal pre-p...
Eligibility Criteria
Inclusion
- Existing diagnosis of type 2 diabetes.
- Admitted to a non-telemetry, non-ICU medicine inpatient bed.
- Willing and able to give informed consent.
- HgbA1c of any value will be accepted.
Exclusion
- Type 1 diabetes
- Admitted to a telemetry, ICU, or non-medicine inpatient bed (e.g., surgery, neurosurgery, obstetrics/gynecology, psychiatry).
- Diabetic ketoacidosis (arterial ph \<7.24, serum bicarbonate \<15, positive serum ketones, anion gap \>12)
- Hyperosmolar hyperglycemic state (blood glucose \>200 mg/dl, serum osmolarity \>320 mOsm/kg)
- Inability to cooperate with study personnel.
- Known allergy or intolerance to detemir or novolog.
- Admission to the hospital \>24 hours from entry into the study.
- Admission to the hospital for inpatient hospice care.
- Admission/continued admission to the hospital for procurement of a guardian.
- Admission/continued admission to the hospital for rehabilitation.
- Patients admitted with the diagnosis of acute coronary syndrome.
- Patients admitted with the diagnosis of acute cerebrovascular accident.
- Patients currently pregnant or breast-feeding.
- Patients not fluent in English or Spanish as it will be difficult to obtained written informed consent in another language.
Key Trial Info
Start Date :
May 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 1 2011
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT00906529
Start Date
May 1 2009
End Date
March 1 2011
Last Update
January 16 2019
Active Locations (1)
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1
Parkland Memorial Hospital
Dallas, Texas, United States, 75235