Status:
COMPLETED
Study of the Effect of Inhaled Anesthetics on Diastolic Heart Function Using a Doppler-derived Efficiency Index
Lead Sponsor:
Washington University School of Medicine
Conditions:
Diastolic Dysfunction
Coronary Artery Disease
Eligibility:
All Genders
18+ years
Brief Summary
The purpose of this study is to determine the effect of inhaled anesthetic drugs upon diastolic heart function (heart suction and filling performance) in patients who are undergoing coronary bypass su...
Detailed Description
Diastolic heart dysfunction is a significant cause of cardiovascular morbidity and is the cause of symptomatic heart failure in approximately one half of patients who are admitted to hospitals with he...
Eligibility Criteria
Inclusion
- Non-emergent coronary bypass grafting surgery
- Left ventricular ejection fraction of 40% or greater
Exclusion
- Myocardial infarction within 4 weeks
- Greater than mild cardiac valvular pathology
- Body mass index greater than 35
- Cardiac dysrhythmias or pacemaker therapy
- Left bundle branch block
- Uncontrolled gastroesophageal reflux disease
Key Trial Info
Start Date :
November 1 2008
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
October 1 2010
Estimated Enrollment :
21 Patients enrolled
Trial Details
Trial ID
NCT00907439
Start Date
November 1 2008
End Date
October 1 2010
Last Update
November 5 2010
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Barnes-Jewish Hospital
St Louis, Missouri, United States, 63110