Status:

COMPLETED

Pharmacokinetics and Safety of Single-Dose Telbivudine in Children and Adolescents With Chronic Hepatitis B

Lead Sponsor:

Novartis Pharmaceuticals

Conditions:

Chronic Hepatitis B

Eligibility:

All Genders

2-18 years

Phase:

PHASE1

Brief Summary

This is a Phase I, open-label, single-dose study to evaluate the pharmacokinetics and safety of LDT600 in pediatric and adolescent patients with chronic hepatitis B infection.

Eligibility Criteria

Inclusion

  • Inclusion Criteria:
  • Children and adolescents patients
  • HBsAg seropositive
  • Exclusion criteria:
  • Decompensated liver disease (Child-Turcotte-Pugh (CTP) Score≥7, Class B and C)
  • Prior anti-HBV therapy within 30 days of study drug dosing.
  • Other protocol-defined inclusion/exclusion criteria may apply.

Exclusion

    Key Trial Info

    Start Date :

    February 1 2009

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ACTUAL

    End Date :

    Estimated Enrollment :

    22 Patients enrolled

    Trial Details

    Trial ID

    NCT00907894

    Start Date

    February 1 2009

    Last Update

    December 19 2020

    Active Locations (7)

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    Page 1 of 2 (7 locations)

    1

    Novartis Investigative Site

    Brussels, Belgium

    2

    Novartis Investigator Site

    Frankfurt, Germany

    3

    Novartis Investigator Site

    Starnberg, Germany

    4

    Novartis Investigator Site

    Wuppertal, Germany