Status:
COMPLETED
Ischemic Preconditioning in Major Hepatectomy
Lead Sponsor:
Assistance Publique - Hôpitaux de Paris
Collaborating Sponsors:
URC-CIC Paris Descartes Necker Cochin
Conditions:
Ischaemic Type Biliary Lesion
Eligibility:
All Genders
18+ years
Phase:
PHASE3
Brief Summary
To evaluate the accuracy of ischemic preconditioning (IPC) as a protective maneuver against ischemia/reperfusion lesion in patients undergoing major liver resection with intermittent portal triad Clam...
Detailed Description
This is a prospective controlled trial, conducted between January 2005 and December 2007. Three centres specialized in hepatobiliary surgery (Cochin hospital (Paris, France), BEAUJON hospital (Clichy,...
Eligibility Criteria
Inclusion
- patients' age ≥ 18 years old,
- liver resection of 3 segments (as described by Couinaud) or more,
- posterior lesionectomy (segment VI and VII),
- liver resection only or associated with a primary digestive or biliary tumor.
- Portal vein embolisation allowed
Exclusion
- Patients with cirrhosis,
- synchronous radiofrequency or cryotherapy ablation,
- undergoing segmentectomy,
- left lateral lesionectomy or laparoscopic liver resection,
- pregnant women
Key Trial Info
Start Date :
September 1 2003
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2008
Estimated Enrollment :
81 Patients enrolled
Trial Details
Trial ID
NCT00908245
Start Date
September 1 2003
End Date
December 1 2008
Last Update
November 20 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Hopital Cochin
Paris, France, 75014