Status:

COMPLETED

Primovist / Eovist in Renally Impaired Patients

Lead Sponsor:

Bayer

Conditions:

Contrast Media

Eligibility:

All Genders

18+ years

Phase:

PHASE4

Brief Summary

Patients with moderate to severe renal impairment scheduled for a magnetic resonance imaging (MRI) scan and injection with a contrast agent, Primovist/Eovist, will be asked to participate. The admini...

Detailed Description

Adverse events data will be reported in Adverse Events section.

Eligibility Criteria

Inclusion

  • Patient must be scheduled for Contrast enhanced magnetic resonance imaging (CE-MRI) of the liver with Primovist/Eovist based on careful risk/benefit evaluation at the recommended dose in one of the approved indications
  • Patient must fulfill criteria for moderate (Estimated glomerular filtration rate \[eGFR\] 30 - 59 mL/min/1.73 m\^2) to severe (eGFR \< 30 mL/min/1.73 m\^2) renal impairment.

Exclusion

  • Gadolinium based contrast agent (GBCA)-enhanced MRI (or administration of a GBCA for any other CE imaging procedure) other than Primovist/Eovist within 12 months prior to administration of Primovist/Eovist
  • History of existing NSF

Key Trial Info

Start Date :

May 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 1 2013

Estimated Enrollment :

357 Patients enrolled

Trial Details

Trial ID

NCT00908596

Start Date

May 1 2009

End Date

July 1 2013

Last Update

July 23 2015

Active Locations (47)

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Page 1 of 12 (47 locations)

1

Los Angeles, California, United States, 90033

2

Jacksonville, Florida, United States, 32209

3

Honolulu, Hawaii, United States, 96813

4

Topeka, Kansas, United States, 66604