Status:
COMPLETED
Vitamin D Supplementation and CD4 Count in HIV-Infected Children
Lead Sponsor:
The Hospital for Sick Children
Conditions:
HIV
Eligibility:
All Genders
1-18 years
Phase:
PHASE2
Brief Summary
To find out if vitamin D supplementing can lead to an improvement in immunological status in HIV-infected children as part of routine clinical care
Detailed Description
The objective of this study is to determine the impact of vitamin D on immunological status in HIV-infected children as measured by CD4 count (CD4 percent). We will determine if vitamin D supplementat...
Eligibility Criteria
Inclusion
- HIV-infected children as defined by ≥ 2 positive HIV DNA PCRs and/or HIV cultures of blood for children less than 18 months of age, or by positive screening and confirmatory serologic testing in those older than 18 months of age
- Stable HIV disease, defined by the absence of change in HIV clinical or immunologic category during the preceding 6 month period, prior to commencing the study
- Age 3 years through 18 years
- Voluntary informed consent
Exclusion
- Any antiretroviral medication change in the 6 months prior to the study, or any anticipated antiretroviral medication change during the duration of the study
- Active participation in another treatment trial
- Serum calcium \< 2mmol/L at baseline
Key Trial Info
Start Date :
February 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 1 2010
Estimated Enrollment :
54 Patients enrolled
Trial Details
Trial ID
NCT00911664
Start Date
February 1 2009
End Date
July 1 2010
Last Update
June 6 2014
Active Locations (1)
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1
The Hospital for Sick Children
Toronto, Ontario, Canada, M5G 1X8