Status:
COMPLETED
Effect of Different Dialysis Dosage on Prognosis in Maintenance Peritoneal Dialysis Patients
Lead Sponsor:
Shanghai Jiao Tong University School of Medicine
Conditions:
End-stage Renal Disease
Eligibility:
All Genders
18-80 years
Phase:
PHASE4
Brief Summary
Peritoneal dialysis (PD) is an important model of renal replacement therapy for end-stage renal disease (ESRD) patients. Thus far, evidence for the initiation dosage of PD treatment is lacking, most p...
Detailed Description
To investigate the effect, feasibility and safety of 6L of dialysate per day after initiation of peritoneal dialysis (PD), we perform a prospective, randomized, controlled, multi-center clinical study...
Eligibility Criteria
Inclusion
- Age from 18 to 80, male or female.
- End stage renal disease patients (eGFR \< 15 ml/min/1.73 m2).
- Maintenance peritoneal dialysis within 6 months after initiation of PD.
- With informed consent.
Exclusion
- Acute renal injury.
- Patients with an expected follow up less than 6 months sch as renal transplantation.
- Transferred from hemodialysis or renal transplantation.
- Residual renal function eGFR less than 1 ml/min.
- HIV positive.
- Cancer patients.
- Unstable organ disease such as active tuberculosis and severe hepatitis. Patients with an expected follow up less than 48 weeks, such as planned kidney transplant.
- Other conditions regarded as unsuitability by investigator, such as pregnancy, severe malnutrition and recent peritonitis.
Key Trial Info
Start Date :
March 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 1 2012
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT00912821
Start Date
March 1 2009
End Date
July 1 2012
Last Update
October 13 2016
Active Locations (1)
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1
Renji Hospital, Shanghai Jiao Tong University school of medicine
Shanghai, China, 200001