Status:
COMPLETED
Effect of Add-on Montelukast to Inhaled Corticosteroids on Airway Responsiveness
Lead Sponsor:
Hvidovre University Hospital
Conditions:
Asthma
Eligibility:
All Genders
18-50 years
Phase:
PHASE4
Brief Summary
Leukotriene receptor antagonists appear to posses additive anti-inflammatory effects to the effect of inhaled corticosteroids. Hypothesis: Treatment with oral montelukast will lower the dose-response...
Eligibility Criteria
Inclusion
- Non-smoking adults with mild to moderate persistent asthma:
- FEV1 \> 70 % pred
- PD20 methacholine \< 3.9 mmol
- treated for at least 3 months with a stable dose of inhaled corticosteroids
- Documented dose-response plateau to inhaled methacholine on two occasions
- Males and non-pregnant females
Exclusion
- Asthma medication other than inhaled corticosteroids and inhaled b2-agonists
- Viral respiratory tract infections within the 3 weeks prior to enrollment
Key Trial Info
Start Date :
August 1 2002
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 1 2006
Estimated Enrollment :
31 Patients enrolled
Trial Details
Trial ID
NCT00913328
Start Date
August 1 2002
End Date
October 1 2006
Last Update
June 4 2009
Active Locations (0)
Enter a location and click search to find clinical trials sorted by distance.
No Results Found
We couldn’t find results for the location/zipcode entered or within the selected range. Please check your input or adjust your search.