Status:
ACTIVE_NOT_RECRUITING
Biomarkers for Pain in Spinal Cord Injury (SCI) Patients
Lead Sponsor:
The University of Texas Health Science Center, Houston
Collaborating Sponsors:
The Institute for Rehabilitaion and Research Foundation
Conditions:
Traumatic Spinal Cord Injury
Neuropathic Pain
Eligibility:
All Genders
18-90 years
Brief Summary
The investigators propose to compare plasma protein profiles for SCI patients with/without chronic neuropathic pain in order identify biomarker(s) that are associated with this medical condition. Seco...
Eligibility Criteria
Inclusion
- A. Chronic Patients
- Inclusion:
- 1\. Two or more years post traumatic SCI with deficit
- Exclusion:
- \< 18 years of age
- Evidence of brain injury on computed tomography (CT) (SCI patients need to be able to comply with completing the pain survey)
- Other medical condition that accounts for chronic pain (i.e. diabetic neuropathy, renal insufficiency, multiple sclerosis, HIV associated neuropathy, alcohol-related neuropathy)
- Temperature \> 100.5°C
- History of infection within the last 30 days (i.e. UTI, URI, pressure sore)
- History of Pulmonary Embolus (PE) or deep vein thrombosis (DVT)
- Inability to obtain informed consent
- Psychiatric problems (patients need to be able to complete the pain survey)
- Diagnosis or treatment of cancer in the last 5 years
- B. Longitudinal, Prospective Cohort Patients:
- Inclusion:
- 1\. Initial traumatic SCI with deficit
- Exclusion:
- Same as listed above C. Healthy Volunteers Healthy volunteers include gender, age and race matched volunteers able to provide informed consent who have,
- No significant medical history (pain free)
- No recent infections
- Take no medications
- Fever free
- Greater than 18 years old
Exclusion
Key Trial Info
Start Date :
June 1 2009
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 1 2030
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT00913471
Start Date
June 1 2009
End Date
December 1 2030
Last Update
August 7 2025
Active Locations (1)
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1
Memorial Hermann Hospital
Houston, Texas, United States, 77030