Status:
UNKNOWN
Comparison of Campath and Rebif Treatment on Cognition in Multiple Sclerosis (MS)
Lead Sponsor:
Washington Neuropsychology Research Group
Collaborating Sponsors:
Genzyme, a Sanofi Company
Conditions:
Relapsing Remitting Multiple Sclerosis
Eligibility:
All Genders
25-50 years
Brief Summary
People with multiple sclerosis (MS) often experience problems with cognitive functioning, which can be debilitating and interfere with their daily functioning. However, research has shown that MS dise...
Detailed Description
The current will use a neuropsychological evaluation capable of detecting the broad range of cognitive difficulties associated with relapsing remitting MS (RRMS). It is a sub-study of an investigation...
Eligibility Criteria
Inclusion
- Diagnosis of relapsing remitting MS and enrollment in Care-MS II trial
- Non-MS controls must be neurologically healthy (with respect to conditions that impact CNS functioning).
- Participants must be between the ages of 25 and 50.
- Corrected vision of subjects must be no worse than 20/50.
- Participants must have at least 10 years of education.
- Participants must be capable of writing and pressing the buttons on a computer mouse.
- Participants must be capable of understanding and following all test instructions.
Exclusion
- Participants with a history of head injury, seizures, or neurological conditions involving the central nervous system (other than MS for the MS groups).
- Participants with upper extremity dysfunction which prohibits them from using a computer mouse.
- Participants who are colorblind.
- Participants with history of psychosis or other severe mental illness.
- Participants with current alcohol/substance abuse.
- Participants taking medications with potential adverse CNS effects
Key Trial Info
Start Date :
March 1 2009
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 1 2011
Estimated Enrollment :
1 Patients enrolled
Trial Details
Trial ID
NCT00914758
Start Date
March 1 2009
End Date
December 1 2011
Last Update
June 5 2009
Active Locations (7)
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1
The Research and Education Institute of Alta Bates Summit Medical Center
Berkely, California, United States, 94705
2
Associates In Neurology. PSC
Lexington, Kentucky, United States, 40513
3
Springfield Neurology Associates, LLC
Springfield, Massachusetts, United States, 01104
4
Dartmouth Medical School/Dartmouth-Hitchcock Medical Center
Lebanon, New Hampshire, United States, 03756