Status:
COMPLETED
Symptom Evaluation After Cessation of a Proton Pump Inhibitor in Healthy Volunteers
Lead Sponsor:
Sahlgrenska University Hospital
Conditions:
Healthy
Eligibility:
All Genders
18-70 years
Phase:
NA
Brief Summary
The purpose of this study is to determine whether proton pump inhibitor (PPI) induced hypersecretion leads to acid related symptoms after treatment in healthy volunteers.
Detailed Description
Treatment with proton pump inhibitors (PPI) has been shown to cause rebound hypersecretion of gastric acid. The clinical significance of this phenomenon is however unclear. This study aims to examine ...
Eligibility Criteria
Inclusion
- Healthy volunteers
- 18-70 years of age
- Informed consent
- No prior history of any GI disorder
Exclusion
- Dyspeptic complaints
- H. pylori infection
- Ongoing treatment with pain-relieving medications (i.e., NSAID)
- Pregnancy or breast feeding
Key Trial Info
Start Date :
January 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 1 2006
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT00915239
Start Date
January 1 2006
End Date
October 1 2006
Last Update
June 5 2009
Active Locations (1)
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1
Sahlgrenska Univeristy Hospital
Gothenburg, Gothenburg, Sweden, 413 45