Status:
COMPLETED
Clinical, Environmental, Neurocognitive, Brain Imaging, and Genetic Validity of Autism and ADHD
Lead Sponsor:
National Taiwan University Hospital
Conditions:
Attention Deficit Hyperactivity Disorder
Autism Spectrum Disorder
Eligibility:
All Genders
8-17 years
Brief Summary
The behavioral patterns, neurocognitive and social impairments, and high heritability are the common characteristics of autism spectrum disorders (ASD) and attention-deficit hyperactivity disorder (AD...
Detailed Description
Specific Aims: 1. To compare the individual phenotypes (emotion/behaviors, attention, impulsivity, etc.), endophenotypes (neurocognitive and social cognitive function, brain imaging), and genotypes, ...
Eligibility Criteria
Inclusion
- Control group: Subjects without ADHD or ASD; ADHD group \& ASD group: subjects have a clinical diagnosis of ADHD, or ASD defined by the DSM-IV, which was made by a full-time board-certificated child psychiatrist at the first visit and following visits.
- Ages range from 7 to 18 when we conduct the study.
- Subjects have at least one biological parent.
- Both parents are Han Chinese.
- subjects and their biological parents (and siblings if any) consent to participate in this study for complete phenotype assessments and blood withdraw for genetic study
Exclusion
- The subjects will be excluded from the study if they currently meet criteria or have a history of the following condition as defined by DSM-IV: Schizophrenia, Schizoaffective Disorder, Organic Psychosis, Mental Retardation, or Pervasive Developmental Disorder. Moreover, the subjects will be excluded from the control group if have a history of the following condition as defined by DSM-IV: ADHD or ASD in addition to the above exclusion criteria.
Key Trial Info
Start Date :
August 1 2010
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
July 31 2013
Estimated Enrollment :
300 Patients enrolled
Trial Details
Trial ID
NCT00916851
Start Date
August 1 2010
End Date
July 31 2013
Last Update
September 2 2021
Active Locations (1)
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1
National Taiwan Univeristy Hospital
Taipei, Taiwan