Status:
COMPLETED
Treatment of Atrophic Nonunion by Preosteoblast Cells
Lead Sponsor:
Jean-Philippe Hauzeur
Conditions:
Pseudarthrosis
Fractures, Ununited
Eligibility:
All Genders
18+ years
Phase:
PHASE1
PHASE2
Brief Summary
Treatment of nonunion, delayed union and malunion fractures of long bones remains problematic. The definition of nonunion is a failure of the fracture to heal in six months in a patient in whom progre...
Detailed Description
We will recruit 30 patients having a atrophic nonunion fracture of long bone present for minimum 6 months.50 ml of bone marrow harvest will be performed under local anaesthesia 3 weeks before the impl...
Eligibility Criteria
Inclusion
- Fracture of a long bone having insufficient healing after minimum 6 months.
- Be able and willing to participate in the study.
Exclusion
- Evidence of malignant disorder in the past five year.
- Patient who is positive for an HIV, hepatitis B or C infection.
- Insufficient reduction of the fracture with displaced fragments.
- Evidence of local sepsis by biological parameters and/or positive isotopic scan using leucocytes labelled by Indium.
Key Trial Info
Start Date :
November 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2009
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT00916981
Start Date
November 1 2008
End Date
June 1 2009
Last Update
February 23 2012
Active Locations (1)
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1
CHU Sart Tilman
Liège, Liège, Belgium, 4000