Status:

COMPLETED

Intranasal Oxytocin for the Treatment of Pain Associated With Interstitial Cystitis

Lead Sponsor:

University of Alabama at Birmingham

Conditions:

Interstitial Cystitis

Eligibility:

All Genders

19-65 years

Phase:

PHASE4

Brief Summary

Anecdotal evidence suggests female patients with painful bladder disorder interstitial cystitis (IC) can experience a significant attenuation of their systems while breastfeeding. Since it has been sh...

Detailed Description

Fifty patients will be enrolled in a double-blinded, placebo-controlled single-dose crossover trial comparing intranasal oxytocin to intranasal saline. At the time of enrollment, patients will complet...

Eligibility Criteria

Inclusion

  • 19 - 65 years of age
  • Must meet the current National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) diagnostic criteria for interstitial cystitis and have some degree of continuous daily pain

Exclusion

  • Pregnancy
  • Under the age of 19
  • Older that the age of 65
  • Breastfeeding women
  • Uncontrolled hypertension
  • History of significant cardiac or pulmonary disease (including arrhythmias)
  • Known allergy to oxytocin
  • Severe psychiatric disease
  • Patients who have undergone procedural interventions within the past month related to their interstitial cystitis

Key Trial Info

Start Date :

June 1 2010

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

September 1 2015

Estimated Enrollment :

25 Patients enrolled

Trial Details

Trial ID

NCT00919802

Start Date

June 1 2010

End Date

September 1 2015

Last Update

May 23 2017

Active Locations (1)

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University of Alabama at Birmingham

Birmingham, Alabama, United States, 35294