Status:

COMPLETED

Alendronate in Juvenile Osteoporosis

Lead Sponsor:

Medical University of South Carolina

Collaborating Sponsors:

FDA Office of Orphan Products Development

Merck Sharp & Dohme LLC

Conditions:

Juvenile Osteoporosis

Low Bone Density

Eligibility:

All Genders

8-21 years

Brief Summary

The investigators earlier have shown that treatment of patients with juvenile osteoporosis with alendronate (Fosamax) for 12 months increased the bone density without side effects. In an open label st...

Detailed Description

With the availability of Dual Energy X-ray Absorptiometry (DXA), juvenile osteoporosis has been recognized and diagnosed in recent years. The disease results from either diminished bone formation or i...

Eligibility Criteria

Inclusion

  • Participated in our earlier clinical study;
  • Completed the earlier open label or double blind study;
  • Availability to participate in the post study;
  • Male and female children who have earlier participated in our clinical trial; AND
  • Parental consent (and patient assent after age 12 years) to participate in the study. Participant's consent for those who have completed 18 years of age and above at the time of clinic visit.

Exclusion

  • Not participated in our earlier clinical study;
  • Not completed our earlier trials; OR
  • Pregnancy.

Key Trial Info

Start Date :

July 1 2009

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

October 1 2010

Estimated Enrollment :

11 Patients enrolled

Trial Details

Trial ID

NCT00920075

Start Date

July 1 2009

End Date

October 1 2010

Last Update

July 11 2018

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Medical University of South Carolina

Charleston, South Carolina, United States, 29425