Status:

COMPLETED

The 4-SITE Field Following Study (4-SITE FF)

Lead Sponsor:

Guidant Corporation

Conditions:

ICD and CRT-D Indicated Patients

Eligibility:

All Genders

18+ years

Brief Summary

The purpose of this study is to evaluate and document appropriate clinical performance of the new 4-SITE Header / Lead interface in the TELIGEN 100 HE 4-SITE (VR and DR) implantable cardioverter defib...

Detailed Description

The following devices will be used (all are CE-marked): * TELIGEN 100 HE 4-SITE (Single and Dual Chamber ICD) * Model Number: F103 (Quadripolar, VR); * Model Number: F111 (Quadripolar, IS-1, DR)...

Eligibility Criteria

Inclusion

  • Study Specific:
  • ICD / CRT-D Indication according to normal clinical practice
  • Patients receiving:
  • a single or dual chamber 4-SITE compatible ICD
  • or a 4-SITE compatible CRT-D
  • one of the RELIANCE 4-SITE defibrillation leads
  • Patients currently implanted with a pacemaker
  • upgraded to a 4-SITE compatible ICD or CRT-D (4-SITE header)
  • one of the RELIANCE 4-SITE defibrillation leads
  • General:
  • Willing and capable of providing informed consent for
  • undergoing a 4-SITE system implant,
  • participating in all testing associated with this clinical investigation at an approved clinical investigational centre and at the intervals defined by this protocol
  • Geographically stable patients who are available for follow-up at a study centre
  • Age 18 or above, or of legal age to give informed consent specific to national law

Exclusion

  • Study Specific:
  • ICD and CRT-D Patients scheduled for a device replacement
  • CRM Patients who have or who would need an lead adaptor
  • All patients who have an active or non-active defibrillation lead other than 4-SITE
  • General:
  • Not willing and not capable of providing informed consent, undergoing a device implant, participating in all testing associated with this clinical investigation (including VT/VF shock conversion) at an approved clinical investigational centre and at the intervals defined by this protocol
  • Patients who were in NYHA Class IV during the last 3 month
  • Patients with pre-existing diseases, which may confound study results
  • Patients currently requiring dialysis,
  • Cancer patients
  • Patients with drug and/or alcohol abuse history
  • Life expectancy \< 12 months (or expected heart transplant within 12 months)
  • Patients on a Heart Transplant List
  • Women who are pregnant or plan to become pregnant. Method of assessment per physician discretion.
  • Enrolled in any other concurrent study

Key Trial Info

Start Date :

May 1 2009

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

January 1 2011

Estimated Enrollment :

430 Patients enrolled

Trial Details

Trial ID

NCT00920452

Start Date

May 1 2009

End Date

January 1 2011

Last Update

December 5 2012

Active Locations (1)

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Bad Oeynhausen Herz- und Diabeteszentrum Nordrhein-Westfalen

Bad Oeynhausen, North Rhine-Westphalia, Germany, D - 32545