Status:

COMPLETED

Vascular Calcification, Inflammation and Coronary Flow Velocity in Hemodialysis Patients

Lead Sponsor:

Istanbul University

Conditions:

Renal Dialysis

Cardiovascular Diseases

Eligibility:

All Genders

18-70 years

Brief Summary

The aim of this cross-sectional study is to determine the correlation of coronary artery calcification as measured by electron-beam computerized tomography and coronary flow reserve measured by trans-...

Detailed Description

Cardiovascular mortality is a major cause of death in end-stage renal disease (ESRD). Therefore, the identification of coronary artery disease (CAD) in ESRD is an important task for nephrologists. Cor...

Eligibility Criteria

Inclusion

  • Subject must be 18 years of age or older and able to give informed consent
  • End stage renal disease patients treated for more than 6 months with hemodialysis

Exclusion

  • Valvular heart disease
  • Prior myocardial infarction
  • Any prior coronary intervention
  • Dilated or hypertrophic cardiomyopathy
  • Congestive heart failure
  • Cardiac arrhythmia
  • Active infection or non-infectious overt inflammation
  • Patients whose LAD could not visualized adequately

Key Trial Info

Start Date :

April 1 2008

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

December 1 2008

Estimated Enrollment :

103 Patients enrolled

Trial Details

Trial ID

NCT00921089

Start Date

April 1 2008

End Date

December 1 2008

Last Update

June 17 2009

Active Locations (1)

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Division of Nephrology, Department of Internal Medicine, Istanbul Faculty of Medicine, Istanbul University

Istanbul, Turkey (Türkiye), 34390

Vascular Calcification, Inflammation and Coronary Flow Velocity in Hemodialysis Patients | DecenTrialz