Status:
COMPLETED
Prevention of Acute Kidney Injury in Cardiac Surgery Patients
Lead Sponsor:
Community Medical Center, Scranton, PA
Conditions:
Kidney Injury
Eligibility:
All Genders
18+ years
Phase:
PHASE2
Brief Summary
Acute kidney injury (AKI) has no uniform criteria, but is commonly defined as an increase in serum creatinine concentration by at least 25% from baseline. It occurs in 30% of patients following cardia...
Detailed Description
This is a randomized, placebo-controlled, prospective, double-blinded. The study will take place at Community Medical Center in Scranton, Pennsylvania. The inclusion criteria are patients undergoing e...
Eligibility Criteria
Inclusion
- elective, urgent, or emergent cardiac surgery using cardiopulmonary bypass
- baseline GFR less than 60 ml/min/1.73m2 estimated using the Modification of Diet in Renal Disease equation
Exclusion
- cardiogenic shock (defined as a cardiac index less 2 L/min/m2 despite high dose inotropes or the need for intra-aortic balloon pump)
- end-stage kidney disease requiring dialysis
- received an infusion of sodium bicarbonate on the same day as cardiac surgery
Key Trial Info
Start Date :
January 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 1 2012
Estimated Enrollment :
92 Patients enrolled
Trial Details
Trial ID
NCT00921518
Start Date
January 1 2009
End Date
January 1 2012
Last Update
April 15 2014
Active Locations (1)
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1
Community Medical Center
Scranton, Pennsylvania, United States, 18510