Status:

WITHDRAWN

Heart & Diabetes - Feasibility Study

Lead Sponsor:

Medtronic Cardiac Rhythm and Heart Failure

Conditions:

Acute Heart Failure

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The main purpose of this study is to validate an intensive protocol of insulin infusion and subsequent subcutaneous insulin administration with the support of continuous glucose monitoring, in additio...

Detailed Description

Heart failure is a common disease (prevalence worldwide: 22 million; incidence worldwide: 2 million; prevalence in Italy: 750.000; incidence in Italy: 170.000), affecting 1-2% of overall population an...

Eligibility Criteria

Inclusion

  • Inclusion Criteria (all of the following inclusion criteria must be met for the patient to be enrolled in the study):
  • acute heart failure, defined according to current ESC Guidelines
  • HbA1c \> 7.5% at admission in Cardiology Unit
  • glycemia \> 180 mg/dL at admission in Cardiology Unit
  • the patients signed the Informed Consent
  • Exclusion Criteria (if any of the following criteria are met, patients cannot be enrolled in the study):
  • heart failure in acute infarction or cardiogenic shock
  • creatinemia \> 3.5 mg/dL at admission or in hemodialytic therapy
  • cirrhosis
  • acute infective pathology
  • cardiac revascularization during the hospitalization or in the preceding 3 months
  • life expectance \< 12 months
  • age \< 18 years
  • pregnant women
  • informed consent not signed
  • subject included in other protocols

Exclusion

    Key Trial Info

    Start Date :

    June 1 2009

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ACTUAL

    End Date :

    September 1 2011

    Estimated Enrollment :

    Patients enrolled

    Trial Details

    Trial ID

    NCT00922402

    Start Date

    June 1 2009

    End Date

    September 1 2011

    Last Update

    July 3 2025

    Active Locations (2)

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    Page 1 of 1 (2 locations)

    1

    Garibaldi Nesima Hospital

    Catania, Italy

    2

    Policlinico S. Matteo

    Pavia, Italy