Status:
TERMINATED
The Effect of Sevoflurane Versus Isoflurane on Vasopressor Need
Lead Sponsor:
UMC Utrecht
Conditions:
Hypotension
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
Aim of this study is to determine the effect of isoflurane versus sevoflurane on blood pressure and systemic vascular resistance.
Detailed Description
In modern anesthesia a variety of volatile anesthetics is available. In cardiac anesthesiology both isoflurane and sevoflurane are frequently used. At present the number of studies comparing the influ...
Eligibility Criteria
Inclusion
- competent adult patients (18 years or older)undergoing elective coronary artery bypass grafting with the use of the cardiopulmonary bypass.
Exclusion
- Patients undergoing valve surgery or combined surgical procedures (e.g. coronary artery bypass grafting in combination with valve reconstruction.
- uncontrolled hypertension
- a poor left ventricular function
- renal failure
- a body mass index of \> 25
- history of cerebrovascular accident, transient ischemic accident or carotid artery stenosis.
Key Trial Info
Start Date :
May 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2009
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT00922844
Start Date
May 1 2009
End Date
December 1 2009
Last Update
April 21 2015
Active Locations (1)
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1
University Medical Center
Utrecht, Utrecht, Netherlands, 3984 CX