Status:
COMPLETED
Influence of Muscular Atrophy on Biological and Functional Benefit of Respiratory Rehabilitation in Patients With Chronic Respiratory Failure
Lead Sponsor:
Centre Hospitalier Universitaire de Saint Etienne
Collaborating Sponsors:
Ministry of Health, France
Conditions:
Respiratory Insufficiency
Eligibility:
All Genders
40-75 years
Phase:
NA
Brief Summary
The prevalence of chronic respiratory failure (CRF) is increasing worldwide and will become the 3rd cause of death by 2020. At the stage of the disease requiring ventilatory assistance, this relates t...
Detailed Description
We therefore propose to explore the effect of a rehabilitation program including endurance and resistance exercises on muscle biopsies. The present study should help to know the molecular pathways im...
Eligibility Criteria
Inclusion
- Prescription of an exercise training program as part of a respiratory rehabilitation
- Existence of an obstructive ventilatory deficit
- Signature of written consent
Exclusion
- Exacerbation of COPD
- Patient with a long-term oxygen therapy
- Active smoker
- Lower limb locomotor limitation preventing to achieve the full respiratory rehabilitation program
- Lower limbs arteritis
- Myocardial infarction or pulmonary embolism of less than 3 months
- Long term anticoagulant
- Type 1 diabetes
Key Trial Info
Start Date :
April 1 2005
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 1 2013
Estimated Enrollment :
32 Patients enrolled
Trial Details
Trial ID
NCT00922857
Start Date
April 1 2005
End Date
September 1 2013
Last Update
July 24 2014
Active Locations (1)
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1
CHU de Saint-Etienne
Saint-Etienne, France, 42055