Status:
COMPLETED
Neurophysiological Targets for Cognitive Training in Schizophrenia
Lead Sponsor:
VA Office of Research and Development
Conditions:
Schizophrenia
Eligibility:
All Genders
18-70 years
Phase:
NA
Brief Summary
The purpose of this study is to determine whether computer-based training of auditory and visual processing results in corresponding improvement in brain function in individuals with schizophrenia.
Detailed Description
Schizophrenia is recognized as one of the leading causes of medical disability worldwide, ranked 9th overall by the World Health Organization, and affects more than 2 million Americans per year. There...
Eligibility Criteria
Inclusion
- DSM-IV diagnosis of schizophrenia or schizoaffective disorder
- Age between 18 \& 70
- minimum of 30 days since discharge from last hospitalization
- minimum of 30 days since last change in psychiatric medications
- receiving mental health services
- no housing changes in the past 30 days
Exclusion
- current diagnosis of alcohol or substance abuse
- history of brain trauma or neurological disease
- chart diagnosis of mental retardation or premorbid intelligence \< 70 based on Wechsler Test of Adult Reading (WTAR) full-scale estimated IQ
- auditory or visual impairment that would interfere with study procedures
- a sample of 20 healthy community volunteers was also recruited according to these criteria and tested, without intervention, as a normative reference sample for MMN and P300 measures
Key Trial Info
Start Date :
November 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 1 2014
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT00923078
Start Date
November 1 2010
End Date
October 1 2014
Last Update
December 22 2017
Active Locations (1)
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1
VA Connecticut Health Care System (West Haven)
West Haven, Connecticut, United States, 06516