Status:
COMPLETED
Sodium Nitrite in Acute Myocardial Infarction
Lead Sponsor:
Johns Hopkins University
Collaborating Sponsors:
Hope Pharmaceuticals
Conditions:
Acute Myocardial Infarction
Eligibility:
All Genders
21-75 years
Phase:
PHASE2
Brief Summary
The purpose of this study is to determine whether the intravenous infusion of sodium nitrite safely prevents ischemia-reperfusion injury in subjects with acute myocardial infarction resulting in impro...
Detailed Description
Despite reperfusion therapies, significant myocardial injury continues to occur from ischemic-reperfusion injury. Studies in animal models of acute myocardial infarction suggest that an infusion of so...
Eligibility Criteria
Inclusion
- Acute ST segment elevation myocardial infarction
- Eligible for percutaneous coronary intervention
Exclusion
- Cardiogenic shock
- Cardiac arrest
- Prior infarct in the infarct related artery
- Hemoglobinopathy, Glucose-6 Phosphate Dehydrogenase (G6PD) deficiency
Key Trial Info
Start Date :
July 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2016
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT00924118
Start Date
July 1 2009
End Date
June 1 2016
Last Update
May 14 2018
Active Locations (3)
Enter a location and click search to find clinical trials sorted by distance.
1
Johns Hopkins Bayview Medical Center
Baltimore, Maryland, United States, 21205
2
Johns Hopkins Hospital
Baltimore, Maryland, United States, 21287
3
University of Massachusetts Medical School
Worcester, Massachusetts, United States, 01655