Status:
UNKNOWN
NON-Invasive Examinations of Coronary Artery Disease
Lead Sponsor:
Herning Hospital
Conditions:
Coronary Artery Disease
Eligibility:
All Genders
18+ years
Brief Summary
The aim of the study is to evaluate and compare the value of 5 different non-invasive diagnostic methods in patients with chest pain suspected for coronary artery disease. The investigators intend to ...
Detailed Description
The aim of the study is to evaluate the diagnostic value of various non-invasive methods. The study is divided into five substudies: Substudy NITRO Purpose: To investigate whether a subjective effec...
Eligibility Criteria
Inclusion
- Intermittent episodes of chest pain (more than two attacks, minimum one attack/week)
- Signed written informed consent
- Sinus rhythm (ECG)
- Age above 18 years
Exclusion
- Previously (known) myocardial infarction or unstable angina with dynamic changes in the ECG or biomarkers (serology)
- CA performed earlier in life
- Known significant cardiac valve disease
- Asthma (not COPD)
- Incapable of performing an exercise test
- Malignant Disease
- Senile dementia or other conditions causing impaired cooperation
- Previous participation in the project
- NTG intolerance
- Pregnancy
- Bundle branch block (QRS \> 120 ms)
- ECG changes:
- Pathologic Q-wave in at least two leads:
- QS-complex or Q-wave \> 0.02 sec. in V2-V3
- QS-complex or Q-wave \> 0.03 sec. and \> 0.1 mV in I, II, aVL, aVF or V4-V6
- Pathologic negative T-wave (in V3-6 and I, II) unless this is part of a left ventricular hypertrophy and strain pattern
- Brady pacemaker
Key Trial Info
Start Date :
January 1 2009
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
January 1 2012
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT00926458
Start Date
January 1 2009
End Date
January 1 2012
Last Update
June 23 2009
Active Locations (1)
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1
Cardiovascular Research Unit, Regionhospital Herning
Herning, Denmark, 7400