Status:

COMPLETED

Antihypertensive Effect of Continuous Positive Airway Pressure in Resistant Hypertensive Patients With Sleep Apnea

Lead Sponsor:

Hospital de Clinicas de Porto Alegre

Conditions:

Hypertension

Eligibility:

All Genders

30-70 years

Phase:

PHASE4

Brief Summary

Obstructive sleep apnea syndrome (OSAS) has been linked to resistant hypertension, but the effect of treatment of OSAS on the resistant hypertension have no been established. In a double-blind randomi...

Detailed Description

This is a double blind, randomized, placebo controlled trial. Participants were consecutive patients with resistant hypertension, defined as uncontrolled BP, despite the concurrent use of 3 or more an...

Eligibility Criteria

Inclusion

  • Clinical diagnosis of resistant hypertension
  • Apnea/hypopnea index \> 15

Exclusion

  • Cardiac surgery on last 3 months
  • Serious arrhythmias
  • Insulin dependent diabetes
  • Debilitating neurological disease
  • severe COPD

Key Trial Info

Start Date :

February 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

April 1 2013

Estimated Enrollment :

45 Patients enrolled

Trial Details

Trial ID

NCT00929175

Start Date

February 1 2008

End Date

April 1 2013

Last Update

February 25 2014

Active Locations (1)

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Hospital de Clinicas de Porto Alegre

Porto Alegre, Rio Grande do Sul, Brazil, 90035003