Status:

TERMINATED

Evaluation of MRI for Prostate Cancer

Lead Sponsor:

Sheba Medical Center

Conditions:

Prostatic Neoplasms

Eligibility:

MALE

18-80 years

Brief Summary

The objective of this study is to evaluate imaging quality and correlation with histopathology in prostate cancer.

Detailed Description

The objective of this study is to evaluate of the potential of endorectal 3T MRI for the staging of prostate cancer before prostatectomy or recurrence of prostate cancer after prostatectomy

Eligibility Criteria

Inclusion

  • Age of patients: up to 80 years.
  • Men scheduled for radical prostatectomy due to prostate cancer or men post radical prostatectomy with suspicion of recurrence.
  • Patients who are able and willing to give consent and able to have an MRI examination.

Exclusion

  • Contraindications to MRI including: claustrophobia, weight over 120 kg, implanted ferromagnetic materials or foreign objects, and known intolerance to the MRI contrast agent (e.g. Gadolinium or Dotarem)
  • Individuals who are not able or willing to tolerate the required prolonged stationary supine position during imaging (approximately 1 hr.)
  • Any rectal pathology preventing probe insertion, (as active proctitis, active ulcerative colitis, fissure ani)
  • Any spinal pathology that prohibits maintaining supine position for an hour
  • Patients with documented myocardial infarction within one month of protocol entry, and patients with cardiac pacemakers
  • Severe cerebrovascular disease (multiple CVA or CVA within 6 months)

Key Trial Info

Start Date :

November 1 2008

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

June 1 2011

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT00930748

Start Date

November 1 2008

End Date

June 1 2011

Last Update

June 27 2011

Active Locations (1)

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Sheba Medical Center

Ramat Gan, Israel