Status:
COMPLETED
Effects of Branched-Chain Amino Acids on Muscle Ammonia Metabolism in Patients With Cirrhosis and Healthy Subjects
Lead Sponsor:
University of Aarhus
Conditions:
Liver Diseases
Hepatic Encephalopathy
Eligibility:
All Genders
35-70 years
Phase:
NA
Brief Summary
The purpose of this study is to determine whether Branched chain Amino Acids enhances the uptake of ammonia in muscle tissue.
Detailed Description
Branched-chain amino acids (BCAA; leucine, valine, isoleucine) are used to prevent hepatic encephalopathy in cirrhotic patients. The main effect of BCAAs is believed to take place in muscles where BCA...
Eligibility Criteria
Inclusion
- 18 patients with liver cirrhosis
- 6 healthy subjects age and sex matched
Exclusion
- Non-treated diabetes
- Pregnancy/breast-feeding
Key Trial Info
Start Date :
November 1 2007
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2009
Estimated Enrollment :
24 Patients enrolled
Trial Details
Trial ID
NCT00931060
Start Date
November 1 2007
End Date
June 1 2009
Last Update
September 15 2009
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