Status:
COMPLETED
Cortisol Activity in Patients With Prader-Willi Syndrome and Healthy Controls
Lead Sponsor:
Children's Mercy Hospital Kansas City
Conditions:
Prader-Willi Syndrome
Eligibility:
All Genders
6+ years
Brief Summary
The purpose of the study is to find out if people with Prader-Willi syndrome have a difference in the protein which changes inactive cortisone to the active stress hormone cortisol.
Eligibility Criteria
Inclusion
- Prader-Willi syndrome confirmed by molecular testing, ages 6 months to adult
- Controls: Age-matched, sex-matched, developmentally normal, BMI-controlled healthy or obese subjects
Exclusion
- PWS subjects without molecular confirmation of the diagnosis
- Subjects receiving glucocorticoid treatment within 3 months of evaluation
- Subjects receiving growth hormone within one year prior to analysis
Key Trial Info
Start Date :
February 1 2009
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
August 1 2010
Estimated Enrollment :
36 Patients enrolled
Trial Details
Trial ID
NCT00932932
Start Date
February 1 2009
End Date
August 1 2010
Last Update
June 27 2011
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