Status:
TERMINATED
Low Dose Extended-release Epidural and Lumbar Plexus Block Compared to Lumbar Plexus Block for Total Hip Resurfacing
Lead Sponsor:
Wake Forest University
Collaborating Sponsors:
EKR Therapeutics, Inc
Conditions:
Hip Arthroplasty
Eligibility:
All Genders
18-65 years
Phase:
PHASE4
Brief Summary
At Wake Forest University, the investigators have been using Extended Release Epidural Morphine (EREM), since late 2004, as part of multimodal analgesia in patients having gynecologic surgeries and hi...
Detailed Description
Extended release epidural morphine (EREM, DepoDur®: Endo Pharmaceuticals, Chadds Ford PA) has been studied and increasingly utilized as a method to allow for the improved post-operative analgesia of e...
Eligibility Criteria
Inclusion
- A primary unilateral Birmingham hip arthroplasty
- Men and women 18-65 years
Exclusion
- Refusal of regional anesthesia
- Laboratory evidence of coagulopathy (platelet count less than 100,000 cells/microliter of blood, prothrombin time greater than 12.1 seconds, partial thromboplastin time greater than 30 seconds, or international normalized ratio of greater than 1.5)
- Allergy to morphine
- Obstructive sleep apnea
- Body mass index (BMI) greater than 40 kg/m2
- Pregnant or lactating
- Severe renal or hepatic disease
Key Trial Info
Start Date :
January 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 1 2013
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT00934661
Start Date
January 1 2010
End Date
March 1 2013
Last Update
September 12 2018
Active Locations (1)
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1
Wake Forest University Baptist Medical Center
Winston-Salem, North Carolina, United States, 27157