Status:
COMPLETED
A Collaborative Model to Improve Blood Pressure (BP) Control and Minimize Racial Disparities
Lead Sponsor:
University of Iowa
Conditions:
Hypertension
Asthma
Eligibility:
All Genders
18+ years
Phase:
PHASE3
Brief Summary
The purpose of the study is to determine the degree to which pharmacist-physician collaborative management (PPCM) of hypertension can be adopted and implemented in clinics with geographic and racial d...
Detailed Description
Blood pressure (BP) is controlled in only 34% of patients with high BP, leading to unnecessary strokes, myocardial infarctions and other cardiovascular events. BP control can be improved with physicia...
Eligibility Criteria
Inclusion
- English or Spanish speaking males or females, over 18 years of age with a diagnosis of hypertension,
- have uncontrolled BP defined as \> 140 mm Hg SBP or \> 90 mm Hg DBP for patients with uncomplicated hypertension; or \> 130 mm Hg SBP or \> 80 mm Hg DBP for patients with diabetes or chronic kidney disease, and
- receive care from one of the participating clinics.
Exclusion
- current signs of hypertensive emergency (acute angina, stroke, or renal failure;
- severe HTN (systolic BP \>200 or diastolic BP \> 114 mm Hg);
- history of MI, stroke, or unstable angina in the prior 6 months;
- systolic dysfunction with a LV ejection fraction \< 35% documented by echocardiography, nuclear medicine study, or ventriculography;
- renal insufficiency, defined by a glomerular filtration rate less than 20 ml/min or previously documented proteinuria \> 1 gram per day;
- significant hepatic disease, including prior diagnoses of cirrhosis, Hepatitis B or C infection, or laboratory abnormalities (serum ALT or AST \> 2 times control or total bilirubin \> 1.5 mg/dl) in the prior 6 months;
- pregnancy;
- diagnoses of pulmonary hypertension or sleep apnea (unless treated by continuous positive pressure ventilation);
- poor prognosis with a life expectancy estimated less than 2 years;
- residence in a nursing home or diagnosis of dementia; and
- inability to give informed consent or impaired cognitive function (defined as \> 3 errors on the 10-item Pfeiffer Portable Mental Status Questionnaire, administered during study intake).
Key Trial Info
Start Date :
January 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 1 2014
Estimated Enrollment :
1441 Patients enrolled
Trial Details
Trial ID
NCT00935077
Start Date
January 1 2010
End Date
March 1 2014
Last Update
July 10 2014
Active Locations (28)
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1
University of California San Diego
San Diego, California, United States, 92093
2
St. Francis Hospital Medical Center
Hartford, Connecticut, United States, 06105
3
University of Florida
Gainesville, Florida, United States, 32601
4
University of South Florida
Tampa, Florida, United States, 33612