Status:
COMPLETED
Assessment of Renal Physiology by Magnetic Resonance Imaging (MRI) in Normal Volunteers
Lead Sponsor:
University Health Network, Toronto
Conditions:
Glomerular Filtration Rate
Renal Blood Flow
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
Estimation of Glomerular Filtration Rate (GFR) is the primary test used to assess patients with renal disease. Although serum creatinine based GFR and nuclear medicine based estimations are routinely ...
Eligibility Criteria
Inclusion
- Healthy male or female volunteers with no known renal disease
- Ages between 18-65 years
- Normal routine urinalysis
- Estimated GFR (eGFR) \>=90mls/min
- Arterial pressure \< 130/85
- No medications (birth control pills and vitamins are acceptable)
Exclusion
- Pregnancy
- Age \<18y or \>65y
- Proteinuria or hematuria as determined by routine urinalysis
- Estimate GFR (eGFR) \< 90 ml/min
- Known history or requirement of treatment for hypertension
- Known allergy to inulin or PAH
- MRI contrast allergy, general contraindications to MRI such as pacemaker, etc.
Key Trial Info
Start Date :
January 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2011
Estimated Enrollment :
24 Patients enrolled
Trial Details
Trial ID
NCT00936416
Start Date
January 1 2010
End Date
December 1 2011
Last Update
January 18 2012
Active Locations (1)
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1
University Health Network
Toronto, Ontario, Canada, M5G 2C4