Status:
COMPLETED
Beef in an Optimal Lean Diet (BOLD) Effects on Metabolic Syndrome
Lead Sponsor:
Penn State University
Collaborating Sponsors:
National Cattlemen's Beef Association, a contractor to the Beef Checkoff
Conditions:
Metabolic Syndrome
Cardiovascular Disease
Eligibility:
All Genders
30-60 years
Phase:
NA
Brief Summary
The proposed research will provide important information about the role of 2 intervention diets that provide different amounts of lean beef and meet current nutrient recommendations for the treatment ...
Eligibility Criteria
Inclusion
- (BMI 27-42 kg/m2)
- Three or more of the following risk factors (defined as having MetSyn):
- abdominal obesity \[waist circumference \> 102 cm (40 inches) in men and \> 88 cm (35 inches) in women\],
- elevated blood glucose \[\> 110mg/dl (6.1 mmol/L)\]
- elevated TG \[\>150 mg/dl (1.7 mmol/L)\]
- low HDL-C \[\<40 mg/dl (1.03 mmol/L) in men and \<50 mg/dL (1.29 mmol/l) in women\]
- hypertension (Systolic Blood Pressure \> 130 mmHg or Diastolic Blood Pressure \> 85 mmHg)\*
- BP medication accepted if BP stable and less than 160/100mm Hg
Exclusion
- A history of myocardial infarction, stroke, diabetes mellitus, liver disease, kidney disease, and thyroid disease (unless controlled on medication)
- Lactation, pregnancy, or desire to become pregnant during the study
- Intake of putative cholesterol-lowering supplements (psyllium, fish oil capsules, soy lecithin, niacin, fiber, flax, and phytoestrogens, stanol/sterol supplemented foods)
- High alcohol consumption (≥ 14 drinks/week)
- Participation in regular physical activity (\> 1 formal session/week)
- Lipid or glucose lowering medication
Key Trial Info
Start Date :
February 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 1 2012
Estimated Enrollment :
63 Patients enrolled
Trial Details
Trial ID
NCT00937638
Start Date
February 1 2009
End Date
March 1 2012
Last Update
August 21 2023
Active Locations (1)
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1
Penn State University
University Park, Pennsylvania, United States, 16802