Status:
COMPLETED
Healthy Fatty Acids in Transition
Lead Sponsor:
Penn State University
Collaborating Sponsors:
California Healthcare Institute
Conditions:
Cardiovascular Disease
Eligibility:
All Genders
30-60 years
Phase:
NA
Brief Summary
Diacylglycerol (DAG) is a molecule that consists of two fatty acid chains bound by ester links to a glycerol molecule, in the form of 1,2 and 1,3 structural isomers. Approximately 10% of the edible oi...
Detailed Description
Commonly consumed vegetable fats and oils are comprised predominantly of TAG, and small amounts of DAG and monoacylglycerol. TAG consists of 3 fatty acid ester, whereas diacylglycerol oil has 2 fatty ...
Eligibility Criteria
Inclusion
- 30-60 years of age
- Moderately elevated LDL-C (120-175 mg/dL) and normal HDL-C (30-50 mg/dL)
- TG \< 350 mg/dL
Exclusion
- Smokers
- A history of myocardial infarction, stroke, diabetes mellitus, liver disease, kidney disease, and thyroid disease (unless controlled on medication)
- Lactation, pregnancy, or desire to become pregnant during the study
- Cholesterol-lowering medications
- Intake of putative cholesterol-lowering supplements (psyllium, fish oil capsules, soy lecithin, niacin, fiber, flax, and phytoestrogens, stanol/sterol supplemented foods)
- Vegetarianism
- Allergic to nuts (Other food allergies will be reviewed on a case-by-case basis)
Key Trial Info
Start Date :
February 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
November 1 2009
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT00937963
Start Date
February 1 2009
End Date
November 1 2009
Last Update
August 21 2023
Active Locations (1)
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1
Penn State University
University Park, Pennsylvania, United States, 16802