Status:
COMPLETED
Optimized Magnetic Resonance Brachytherapy (MR BT) in Cervix Cancer
Lead Sponsor:
University Health Network, Toronto
Collaborating Sponsors:
Princess Margaret Hospital, Canada
Conditions:
Cervix Cancer
Eligibility:
FEMALE
18+ years
Phase:
PHASE2
Brief Summary
Patients with cervix cancer usually require external radiation given to the whole pelvis then an internal radiation boost, also called brachytherapy, to treat any remaining tumour. Standard brachyther...
Detailed Description
Pre-treatment: Prior to examination under anaesthesia and placement of the intra-uterine applicator, in addition to standard assessment of treatment toxicity, the patient may complete an optional Sexu...
Eligibility Criteria
Inclusion
- Age over 18 years
- ECOG performance status 0-2
- Histological confirmed carcinoma cervix
- Decision to treat with EBRT (+/- concurrent chemotherapy), and PDR BT
- Ability to comply with study protocol
- Patient informed consent
Exclusion
- Unable to or unwilling to give informed consent
- Not suitable for intra-uterine brachytherapy
- Previous treatment for pelvic malignancy
- Previous pelvic radiotherapy
- Serious claustrophobia
- Previous history of metallic injury to the eye
- Non-removable implants contraindicated for MRI
- Cardiac pacemaker
- Other contraindication to MRI -Pregnancy, lactation or child-bearing potential without adequate contraception -
Key Trial Info
Start Date :
May 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
January 1 2017
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT00938106
Start Date
May 1 2008
End Date
January 1 2017
Last Update
October 20 2022
Active Locations (1)
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1
University Health Network
Toronto, Ontario, Canada, M5G 2M9