Status:

COMPLETED

Reactogenicity and Safety of GlaxoSmithKline (GSK) Biologicals' Rotarix™ (Human Rotavirus Vaccine) in Indian Infants

Lead Sponsor:

GlaxoSmithKline

Conditions:

Infections, Rotavirus

Eligibility:

All Genders

6-167 years

Brief Summary

This post marketing surveillance will evaluate reactogenicity and safety data of human rotavirus vaccine when administered to healthy infants according to the Prescribing Information in India.

Eligibility Criteria

Inclusion

  • Subjects who the investigator believes that their parents/guardians can and will comply with the requirements of the protocol should be enrolled in this PMS.
  • A male or female infant, from the age of 6 weeks at the time of the first vaccination and less than 24 weeks of age at the time of second vaccination.
  • Written informed consent obtained from the parent or guardian of the subject.

Exclusion

  • History of allergic disease or reactions likely to be exacerbated by any component of the vaccine.
  • Concurrently participating in another clinical study, at any time during the surveillance period, in which the subject has been or will be exposed to an investigational or a non-investigational product (pharmaceutical product or device).
  • Acute disease at the time of enrolment.
  • Any history of uncorrected congenital malformation of the gastrointestinal tract that would predispose the subject for intussusception.
  • Known hypersensitivity after previous administration of rotavirus vaccine or to any component of the vaccine.
  • Gastroenteritis within 7 days preceding vaccination.

Key Trial Info

Start Date :

August 3 2009

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

April 23 2010

Estimated Enrollment :

332 Patients enrolled

Trial Details

Trial ID

NCT00938327

Start Date

August 3 2009

End Date

April 23 2010

Last Update

January 2 2018

Active Locations (12)

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Page 1 of 3 (12 locations)

1

GSK Investigational Site

Bangalore, India, 560 011

2

GSK Investigational Site

Bangalore, India, 560 095

3

GSK Investigational Site

Chennai, India, 600 033

4

GSK Investigational Site

Delhi, India, 110085

Reactogenicity and Safety of GlaxoSmithKline (GSK) Biologicals' Rotarix™ (Human Rotavirus Vaccine) in Indian Infants | DecenTrialz