Status:
UNKNOWN
Hypofractionated Intensity Modulated Chemoradiotherapy to Treat Locally Advanced Non-Small Cell Lung Cancer
Lead Sponsor:
National University Hospital, Singapore
Collaborating Sponsors:
Tan Tock Seng Hospital
Conditions:
Stage III Non-Small Cell Lung Cancer
Eligibility:
All Genders
21-70 years
Phase:
PHASE2
Brief Summary
Locally advanced non-small cell lung cancer can be treated successfully with chemotherapy and radiation. However, the cure rate is low. This study is carried out to find out whether giving radiothera...
Eligibility Criteria
Inclusion
- Pathologically proven (either histologic or cytologic) diagnosis of Stage IIIA or IIIB non-small cell lung cancer; excluding patients with N3 disease based on supraclavicular or contralateral hilar adenopathy, or significant pleural / pericardial effusion.
Exclusion
- Patients for whom treatment is planned with a maximum dose of ≥ 66 Gy to the ipsilateral brachial plexus
- Greater than minimal, exudative, or cytologically positive pleural effusions
- ≥ 10% weight loss within the past month
- Prior invasive malignancy (with exceptions)
- Prior radiotherapy to the region of the study cancer
- Significant co-morbidities
- Pregnancy or women of childbearing potential and men who are sexually active and not willing/able to use medically acceptable forms of contraception
- Known allergic reactions to components of planned chemotherapy regimen
Key Trial Info
Start Date :
July 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
Estimated Enrollment :
43 Patients enrolled
Trial Details
Trial ID
NCT00938418
Start Date
July 1 2009
Last Update
July 13 2009
Active Locations (3)
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1
National University Hospital
Singapore, Singapore
2
National University Hospital
Singapore, Singapore
3
Tan Tock Seng Hospital
Singapore, Singapore