Status:
COMPLETED
Effects of Intravenous Infusions of Gut Hormones on Appetite and Metabolism.
Lead Sponsor:
University of Copenhagen
Conditions:
Obesity
Eligibility:
MALE
18-50 years
Phase:
NA
Brief Summary
The purpose of this study is to investigate the effects of intravenous infusion of two gastrointestinal hormones, PYY3-36 and GLP-1, alone and in combination, on appetite in healthy obese men. The inv...
Eligibility Criteria
Inclusion
- Men age 18-50 years
- BMI ≥30
- healthy
Exclusion
- Diabetes mellitus
- psychological illness
- on special diets (eg vegetarian, Atkins)
- weight change of \>3kg within the 2 months prior to screening
- Hypothalamic or genetic aetiology of obesity
- diagnosed cancer
- chronic illness or disease
- Eating disorder (anorexia or bulimia)
- smoking
- substance abuse
- Use of any prescription or over the counter medication that can affect metabolism
- Excessive intake of alcohol (\>7 drinks/week)
- Excessive intake of caffeine (\>300 mg/day)
- High level of physical activity (\>10 hours/week)
- Lack of desire or willingness to take part in and follow study protocol
Key Trial Info
Start Date :
March 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 1 2012
Estimated Enrollment :
24 Patients enrolled
Trial Details
Trial ID
NCT00940134
Start Date
March 1 2011
End Date
January 1 2012
Last Update
June 15 2012
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Department of Human Nutrition, Faculty of Life Sciences, University of Copenhagen
Copenhagen, Denmark, 1958