Status:
COMPLETED
Dopaminergic Loss and Pain in Parkinson's Disease
Lead Sponsor:
University Hospital, Toulouse
Conditions:
Parkinson's Disease
Pain
Eligibility:
All Genders
30-70 years
Phase:
PHASE2
Brief Summary
About 46% of patients suffering from Parkinson's disease present pain disorders. Parkinson disease is characterized by loss of dopaminergic neurons. The aim of this study is to assess the relationship...
Detailed Description
Parkinson's disease is a frequent neurodegenerative disease leading to motor handicap, cognitive and pain disorders. These pain disorders could be correlated to dopaminergic loss. The clinical trial ...
Eligibility Criteria
Inclusion
- Patients with clinically established Parkinson's disease according to the UKPDSBB (UK Parkinson's Disease Society Brain Bank) (Gibb et Less, 1998; Hugues et al, 1992).
- Male or Female patients, aged from 30 to 70 years.
- Patients must benefit from the French Social security system.
- Patients must give a written informed consent.
- Female fertile patients must use an efficient method of contraception.
- If patients suffer from chronic pain, pain must be related to Parkinson's disease.
Exclusion
- Patients with a syndrome other than the idiopathic Parkinson's disease.
- Patients suffering from important trembling during the OFF periods or abnormal involuntary movements (dyskinesia) during the ON periods, not allowing the imagery exam to be performed.
- Patients suffering from another disease causing chronic pain.
- Patients suffering from cancer.
- Patients with cognitive dysfunction.
- Patients not able to complete the scales.
- Pregnant, breastfeeding or fertile female patients not using an efficient method of contraception.
- Patients not willing to participle in the trial.
Key Trial Info
Start Date :
March 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 1 2010
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT00940914
Start Date
March 1 2009
End Date
July 1 2010
Last Update
July 29 2020
Active Locations (1)
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1
University Hospital Toulouse
Toulouse, France, 31059