Status:

COMPLETED

Effect of Dietary Fat Type in Combination With High Protein on Plasma Homocysteine Levels

Lead Sponsor:

Malaysia Palm Oil Board

Collaborating Sponsors:

International Medical University (IMU), Kuala Lumpur,Malaysia

Conditions:

Healthy

Eligibility:

All Genders

20-60 years

Phase:

NA

Brief Summary

In this study, the investigators address the research question of whether palm olein will have a positive influence on plasma total homocysteine levels in human volunteers provided with high-protein d...

Detailed Description

The experimental are comprise of 30% kcal fat, 20% kcal protein and 50% kcal carbohydrate. Each of the test fat \[palm olein (POo), virgin olive oil (OO) and coconut oil (CO)\] contributes to two-thir...

Eligibility Criteria

Inclusion

  • Apparently healthy adult males and females aged 20-60 years, with BMI 23.0 -29.9 kg/m2, and free from any disease (will be decided through history taking, physical examination and biochemical tests).
  • Not on any medication or treatment associated with reduction of CHD.
  • Non-smokers and non heavy drinker or having smoking or alcoholic history.
  • Not pregnant or lactating.
  • Willing to adhere to the Dietary Guidelines to the study.

Exclusion

  • Obese \[Body Mass Index (BMI) ≥ 30\] or grossly underweight (BMI \< 18).
  • Suffering from chronic diseases such as diabetes mellitus, CHD, cancer or any liver/renal disease.
  • People with blood clotting problem.
  • Hypertensive persons (systolic pressure \> 140 mmHg, diastolic pressure \> 90 mmHg)

Key Trial Info

Start Date :

February 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 1 2010

Estimated Enrollment :

45 Patients enrolled

Trial Details

Trial ID

NCT00941837

Start Date

February 1 2009

End Date

October 1 2010

Last Update

June 8 2011

Active Locations (1)

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Malaysian Palm Oil Board

Kajang, Selangor, Malaysia, 43000