Status:

COMPLETED

A Study of Triple-site Ventricular Pacing in Patients Who Have Not Responded to Conventional Dual Ventricular Site Cardiac Resynchronization Therapy

Lead Sponsor:

University Hospitals, Leicester

Conditions:

Heart Failure

Eligibility:

All Genders

18+ years

Phase:

PHASE4

Brief Summary

Patients are randomised to receive ongoing optimised device and medical therapy or triple ventricular site resynchronisation. The hypothesis states that patients receiving triple-site resynchronizatio...

Eligibility Criteria

Inclusion

  • Implanted with a CRT device \> 6 months previously according to current and conventional CRT indications
  • Device optimization \> 1 months previously
  • Aged 18yrs or older
  • Able to attend outpatient follow up

Exclusion

  • Recent MI (\<2 months)
  • Women who are pregnant or planning pregnancy
  • Severe co morbid illness (where patients are not expected to survive duration of follow up period or where repeated outpatient visits may not be in best interest of patients)
  • Upgrade procedure is contraindicated for safety reasons.
  • Class IV inotropic agents
  • Patient unwilling to comply with required follow-up protocol including randomization scheme

Key Trial Info

Start Date :

July 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

November 1 2012

Estimated Enrollment :

20 Patients enrolled

Trial Details

Trial ID

NCT00941850

Start Date

July 1 2009

End Date

November 1 2012

Last Update

December 8 2015

Active Locations (1)

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1

University of Leicester HNS trust

Leicester, England, United Kingdom, LE3 9QP