Effect of Lactose, Fructose, Sucrose, Whey Protein, and Soy Protein on Substrate Absorption and Oxidation: a Pilot Study

Status:

COMPLETED

Effect of Lactose, Fructose, Sucrose, Whey Protein, and Soy Protein on Substrate Absorption and Oxidation: a Pilot Study

Lead Sponsor:

United States Department of Agriculture (USDA)

Conditions:

Substrate Absorption

Substrate Oxidation

Eligibility:

MALE

25-65 years

Phase:

Brief Summary

Does the consumption of various combinations of mono and disaccharides (lactose, sucrose and fructose) and protein isolates (whey or soy) result in altered substrate absorption, substrate oxidation, a...

Detailed Description

Epidemiological research has shown that dairy products aid in weight loss and weight maintenance. Some evidence suggests that this effect is due to the whey component (which contains whey proteins and...

Eligibility Criteria

Inclusion

Male.
BMI at least 20 and less than 38 kg/m2 and body weight \< 300 lbs.
Age 25 to 65 years at beginning of study.
Fasting glucose \< 126 mg/dL.
Blood pressure \< 160/100 mm Hg.
Total plasma cholesterol \< 280 mg/dL.
Nonsmokers or tobacco users (for at least 6 months prior to the start of the study.)

Exclusion

History or presence of kidney disease, liver disease, gout, certain cancers, thyroid disease, gastrointestinal, other metabolic diseases, or malabsorption syndromes.
Type 2 diabetes requiring the use of oral antidiabetic agents or insulin.
History of eating disorders.
Volunteers who routinely participate in heavy exercise or volunteers who initiate an exercise program during the study.
Volunteers who have lost 10% of body weight within the last 12 months .
Volunteers who have been on Atkins, South Beach or similar diet in 3 months prior to start of study.
Use of prescription or over-the-counter antiobesity medications or supplements (e.g., phenylpropanalamine, ephedrine, caffeine, during and for at least 6 months prior to the start of the study).
Known (self-reported) allergy or adverse reaction to dairy products (including lactose) or soy.
Volunteers who consume whey or soy protein supplements.

Key Trial Info

Start Date :

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

Estimated Enrollment :

9 Patients enrolled

Trial Details

Trial ID

NCT00942513

Last Update

February 9 2011

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