Status:
COMPLETED
High Resolution Phenotyping in Healthy Humans
Lead Sponsor:
Mayo Clinic
Collaborating Sponsors:
National Heart, Lung, and Blood Institute (NHLBI)
Conditions:
Pressor Response
Baroreflex Sensitivity
Eligibility:
All Genders
18-50 years
Brief Summary
Baroreflex sensitivity is integral to blood pressure regulation, and varies among healthy, normotensive individuals. A reduced compensatory ability of baroreflex buffering in patients with carotid den...
Detailed Description
Growing evidence suggests an association of environmental stress with the development of hypertension and there is strong evidence in normotensive subjects that a greater pressor response to sympathoe...
Eligibility Criteria
Inclusion
- Men age 18-40
- Non-pregnant women age 18-50
Exclusion
- Any medical conditions affecting the cardiovascular system
- Any prescribed chronic medications (except contraceptives)
- Extremes of fitness (not totally sedentary, not highly exercise-trained)
- BMI greater than 28
Key Trial Info
Start Date :
April 1 2006
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
February 1 2013
Estimated Enrollment :
300 Patients enrolled
Trial Details
Trial ID
NCT00943774
Start Date
April 1 2006
End Date
February 1 2013
Last Update
January 6 2016
Active Locations (1)
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1
Mayo Clinic
Rochester, Minnesota, United States, 55905