Status:
TERMINATED
Impaired Insulin-like Growth Factor-1 (IGF-1) Generation Causes Protein Catabolism and Poor Growth in Children With Crohn Disease
Lead Sponsor:
Nationwide Children's Hospital
Conditions:
Crohns Disease
Eligibility:
All Genders
5-15 years
Brief Summary
The investigators will prospectively recruit 26 children with moderate - severe active Crohn disease (PCDAI \>30). Results will be compared to 26 patients in sustained remission (PCDAI \<10 and physic...
Eligibility Criteria
Inclusion
- Diagnosed with Crohn disease by endoscopy and histologic samples
- Chronological and/or bone age 6-15 years old
- Tanner 1 - 2
- Willing to participate in our longitudinal evaluation
Exclusion
- Concomitant persistent chronic infectious disease
- Inflammatory bowel disease not diagnosed as Crohn disease
- Immunological disorder (excluding Crohn disease)
- Associated severe concomitant chronic illnesses (CF, liver failure)
- Pregnancy
Key Trial Info
Start Date :
July 1 2009
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
May 1 2010
Estimated Enrollment :
1 Patients enrolled
Trial Details
Trial ID
NCT00946361
Start Date
July 1 2009
End Date
May 1 2010
Last Update
May 15 2015
Active Locations (1)
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1
Nationwide Children's Hospital
Columbus, Ohio, United States, 43205