Status:
COMPLETED
Trial of Aripiprazole in Trichotillomania
Lead Sponsor:
Stanford University
Conditions:
Trichotillomania
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
No medication has been reliably shown to benefit those suffering from trichotillomania (compulsive hair pulling). The current study proposes to evaluate the effectiveness of the medication aripiprazol...
Detailed Description
The proposed study is an 8-week, open-label trial of aripiprazole. The study would enroll 10 patients diagnosed with TTM meeting DSM-IV criteria. Subjects would start at a dose of 5 mg, which can be r...
Eligibility Criteria
Inclusion
- Eligible patients:
- Must be outpatients between the ages of 18 and 65 at the start of study
- May be male or female
- Have DSM-IV trichotillomania of at least 6 months duration
- Allowed psychotropic medications are limited to:
- SSRIs (citalopram, escitalopram, fluoxetine, fluvoxamine, paroxetine, sertraline), SNRIs (duloxetine, venlafaxine) and mirtazapine, as long as the dosage has not changed for 4 weeks prior to study enrollment.
- Other allowed medications include non-hypnotic sleeping agents, specifically trazodone, diphenhydramine, hydoxyzine and ramelteon.
- If a patient is taking non-allowed psychotropic medications, he/she must be titrated off by the prescribing physician and be off of the medication for at least 2 weeks prior to trial enrollment.
- We will not exclude patients meeting DSM-IV criteria for:
- body dysmorphic disorder;
- major depression;
- dysthymia;
- GAD, social phobia, panic disorder.
Exclusion
- We will exclude patients suffering from:
- organic mental disorders;
- psychotic mental disorders including delusional disorder, somatic type;
- mental retardation or developmental disabilities;
- substance or alcohol abuse;
- depressive disorders with current suicidal risk;
- factitious disorders;
- dissociative disorders;
- obsessive compulsive disorder;
- personality disorders sufficiently severe to interfere with cooperation with the study;
- bipolar I or II disorder.
- Patients taking psychotropic agents other than those specifically listed in item d above. If a patient is taking non-allowed psychotropic medications, he/she must be titrated off such medications by the prescribing physician and be off of the medication for 2 weeks prior to trial enrollment.
- Pregnant or nursing women.
- Patients with a known hypersensitivity or allergy to aripiprazole.
Key Trial Info
Start Date :
July 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 1 2010
Estimated Enrollment :
12 Patients enrolled
Trial Details
Trial ID
NCT00947154
Start Date
July 1 2009
End Date
July 1 2010
Last Update
June 16 2015
Active Locations (1)
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1
Stanford University School of Medicine
Stanford, California, United States, 94305