Status:
WITHDRAWN
Study of the Brain Stimulation Effect on Memory Impairment in Alzheimer Disease
Lead Sponsor:
Centre Hospitalier Universitaire de Nice
Conditions:
Memory Disorders
Eligibility:
All Genders
50-70 years
Phase:
NA
Brief Summary
Alzheimer's Disease (AD) is the most common cause of dementia. Today no treatment had shown consistent efficacy to stop or slow down the disease. Recent report of enhancement of memory abilities by bi...
Detailed Description
Alzheimer's Disease (AD) is the most common cause of dementia whom estimated prevalence rise to more than 5 millions in the US. AD patients display progressive impairment of episodic memory and instru...
Eligibility Criteria
Inclusion
- Patients between 50 and 65 years of age,
- Patients with Alzheimer disease (according to DSM-IV criteria)
- Recent diagnosis of Alzheimer disease (less than 2 years ago)
- Patients with a total score in "Mini Mental Test" between 20 and 24.
- Patient with impaired performance of their occasional memory, estimated by the test of Grober and Buschke (according to the standards, according to the age, the sex and the sociocultural level).
- Patients covered by Social Security
- Patients willing to sign the proper consent forms
Exclusion
- associated DSM I axis pathology,
- contra-indication to surgery or MRI,
- preoperative MRI abnormalities
- Withdrawal of patient consent
- Study sponsor or investigator decision to suspend the study.
- Diagnosis of a metabolic or hormonal disorder on the biological assessment realized during the inclusion.
Key Trial Info
Start Date :
August 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 1 2012
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT00947934
Start Date
August 1 2009
End Date
August 1 2012
Last Update
April 12 2024
Active Locations (2)
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1
CMR2 Hôpital de Cimiez
Nice, France, 06001
2
Service de Neurochirurgie Hôpital Universitaire de Pasteur
Nice, France, 06100