Status:

COMPLETED

CP-868,596 And CP-868,596 Plus AG-013736 In Combination With Docetaxel In Advanced Solid Tumors

Lead Sponsor:

Arog Pharmaceuticals, Inc.

Conditions:

Advanced Solid Tumors

Eligibility:

All Genders

18+ years

Phase:

PHASE1

Brief Summary

A5301005 is a phase 1 study in patients with solid tumors which is testing the safety and tolerability of adding targeted agents to a standard chemotherapy. CP-868,596 is a platelet-derived growth fac...

Eligibility Criteria

Inclusion

  • Be ≥18 years old and with histologically or cytologically confirmed advanced solid tumors refractory/resistant to currently available therapies or for which there is no standard therapy.
  • Patients with primary brain tumors are not eligible.
  • Have at least one site of measurable disease.

Exclusion

  • Received chemotherapy (including targeted agents such as erlotinib), radiotherapy, immunotherapy or any investigational therapy within 3 weeks of study entry (within 6 weeks for previous treatments with nitrosoureas or mitomycin C).
  • Received tamoxifen within 4 weeks prior to study entry.

Key Trial Info

Start Date :

December 1 2005

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 1 2008

Estimated Enrollment :

50 Patients enrolled

Trial Details

Trial ID

NCT00949624

Start Date

December 1 2005

End Date

June 1 2008

Last Update

January 19 2012

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Pfizer Investigational Site

Durham, North Carolina, United States, 27710

2

Pfizer Investigational Site

East Melbourne, Victoria, Australia, 3002