Status:
COMPLETED
Cytokine-Associated Depression and Social Pain
Lead Sponsor:
University of California, Los Angeles
Conditions:
Depression
Eligibility:
All Genders
18-45 years
Phase:
EARLY_PHASE1
Brief Summary
Recent research has demonstrated a relationship between depression and immune system activity, specifically proinflammatory cytokine activity. Although experimentally-induced immune activation leads t...
Eligibility Criteria
Inclusion
- right-handed
Exclusion
- 1\) BMI greater than 30,
- 2\) presence of physical health problems or medication use,
- 3\) evidence of an Axis I psychiatric disorder based on the SCID assessment,
- 4\) evidence of recreational drug use from a positive urine test,
- 5\) positive pregnancy test, if female,
- 6\) abnormalities on screening laboratory tests (blood cell count, liver function),
- 7\) claustrophobia,
- 8\) metal in body,
- 9\) history of allergies, autoimmune, liver, or other severe chronic diseases,
- 10\) current use of prescription medications,
- 11\) nightshift work or time zone shifts (\> 3hrs) within the previous 6 weeks.
Key Trial Info
Start Date :
January 1 2007
Trial Type :
INTERVENTIONAL
End Date :
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT00949845
Start Date
January 1 2007
Last Update
July 30 2009
Active Locations (1)
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1
UCLA General Clinical Research Center
Los Angeles, California, United States, 90095