Status:

COMPLETED

Therapy Targeting Depression and HIV Treatment Adherence (The TRIAD Study)

Lead Sponsor:

Massachusetts General Hospital

Collaborating Sponsors:

National Institute of Mental Health (NIMH)

Conditions:

HIV

Depression

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

This study will test a therapy for both helping people adhere to their HIV medication regimens and treating them for depression.

Detailed Description

People infected with HIV are more likely to suffer from depression than those not infected, with studies finding anywhere from 20% to 50% of HIV-infected individuals having significant depressive symp...

Eligibility Criteria

Inclusion

  • HIV-infected
  • Current diagnosis of depression or prescribed an antidepressant medication with at least some residual symptoms (e.g., clinical global impressions \[CGI\] scale score of 2 or greater)
  • Prescribed a stable regimen of highly active antiretroviral therapy (HAART) for HIV for at least 2 months

Exclusion

  • Active, untreated, and unstable major mental illness (i.e., untreated psychosis or mania) that would interfere with cognitive behavioral therapy (CBT) treatment for depression
  • Diagnosis with any primary psychotic disorder, even if treated
  • Treatment with CBT within the past year

Key Trial Info

Start Date :

September 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

April 1 2013

Estimated Enrollment :

240 Patients enrolled

Trial Details

Trial ID

NCT00951028

Start Date

September 1 2008

End Date

April 1 2013

Last Update

June 18 2013

Active Locations (4)

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Page 1 of 1 (4 locations)

1

Massachusetts General Hospital

Boston, Massachusetts, United States, 02114

2

Fenway Community Health Center

Boston, Massachusetts, United States, 02215

3

Butler Hospital

Providence, Rhode Island, United States, 02906

4

The Miriam Hospital

Providence, Rhode Island, United States, 02906